Based on the current severe and complex anti-corruption situation in universities, this article further strengthens the education of party conduct and integrity, and improves the ability of party members and cadres to resist corruption and prevent change; Further strengthen and improve the supervision and restraint mechanism to promote the construction of a clean government; Further increase the intensity of case investigation and fully fulfill the responsibilities of disciplinary accountability; Further strengthening self construction, serving the overall situation of school reform and development, and discussing the specific connotations of strengthening supervision, strict discipline enforcement, and serious accountability, combined with the nature of their own work, explored and studied the strengthening of disciplinary inspection and supervision work in universities under the new situation.